DNA Problem Solving – Using Genetic Genealogy to Find Answers

by Lisa Cooke | Feb 24, 2021 | 01 What's New, DNA, Elevenses with Lisa | 3 comments

Elevenses with Lisa Episode 44 Show Notes

Do you have a DNA problem?

Maybe it’s as simple as having a ton of matches and not knowing what to do with them. How do you keep track of all those matches. How to you know which matches to focus on? How can you can use all your matches to do what you really want to do, which is learn more about my family history?

In this episode of Elevenses with Lisa we are visiting with someone who has worked past many of those problems. She uses her DNA matches to solve some of her genealogical questions and the questions of her patrons. Today she’s here to help you!

My special guest is Sara Allen, a librarian at the Genealogy Center at the Allen County Public Library. I wanted to talk to Sara because she’s not a biologist, or a Genetic Genealogy Guru. She’s like you and me: she’s passionate about family history! She shares genetic genealogy with folks in a very practical, and easy-to-understand way.

As a side note, we were lucky to record this episode because the day Sara and I were to meet to record the library was closed due to a snow storm. I’m in Texas and we’re buried in a deep freeze with devastating power outages, and at our house, no water for a time. But we moved things around and got it done. However, in all the chaos I managed to put my microphone on the wrong setting, so I’m going to sound like I’m sitting in a Folgers coffee can. But that doesn’t matter because it is what Sara has to say that’s really important.

Oh, and they were also doing construction at the library the day we finally recorded, so it’ll sound occasionally like we use jack hammers on our DNA! However, neither snow nor ice nor lack of water nor construction zones will keep us (as your faithful genealogists) from the swift completion of this appointed show.

Special Guest: Sara Allen, Librarian, Genealogy Center at Allen County Public Library, Fort Wayne, IN
Email: genealogy@acpl.info

How to Start Solving Genealogical Problems with DNA

Sara shared her basic over-arching plan for using DNA to answer a genealogical question:

First, do comprehensive traditional genealogical research on the problem.
Then do DNA testing.
Follow the clues where they lead.
Use the genealogical proof standard to come to an accurate conclusion/solution. Also view the DNA standards.

Then she shared the specific steps for her research plan.

Research Plan for Solving Genealogical Problems with DNA

Identify your research problem.
Summarize genealogical research results.
Choose most relevant DNA test/tests to order.
Choose the most helpful family member(s) to test. These are people who carry the particular DNA that falls you will need.
Complete the rest of your family tree to at least 4^th great grandparents (4GG) if possible.

Choosing the Right DNA Test

Step 3 was to choose the most relevant DNA test. This is important because there are three main kinds of tests out there. Each has strengths and weaknesses. Understanding what each test is capable of is key to getting the results you need.

Autosomal test – autosomal DNA is inherited 50/50 from mother and father. Both men and women can be tested. Start with this test, unless your mystery goes farther back than 5-6 generations of great grandparents.
Y Chromosome test – only males can test. It tests a man’s direct paternal line.
Mitochondrial (mtDNA) test – Both men and women inherit Mitochondrial DNA and can be tested for it. However, it’s important to understand that only women can pass it on to the next generation. Follow the line of potential inheritance in order to identify the right person to test. The Mitochondrial test tests the direct maternal line only.

How to Choose the Best Family Member to DNA Test

If you’ve decided that an Autosomal DNA test is what you need, a relative one or two generations older (on the correct side of the family) is always better. Examples: Parents, Aunts/Uncles, Grandparents, Great-aunts/uncles, Parent’s first cousin

If you’re going to do a Y or mtDNA, choose a family member who falls within the correct path of DNA inheritance.

Sorting DNA Matches

Sort your matches out by family line or common ancestor couple.
View your match’s name, family tree or family names, and shared matches to help you sort into family lines.
Use known cousins to help you sort. If you are related to a cousin in only one way, then your “shared matches” with that cousin should be “relatives” on the same side of the family as the cousin.
Sara uses color coding dots to stay organized and detangle matches.

If there is a family tree, copy it, either electronically or print it out on paper. Compare and contrast trees looking for common names, common ancestor couples, common places. Work on establishing relationship between the different matches based on their trees. In other words, do genealogy!

Case #1: Who Were the Parents of Dovey Renolds Allen?

Here’s an outline of the case Sara covers in this episode so you can follow along.

Step 1: Define the Problem

Dovey Reynolds was born around 1822 in North Carolina and was married in 1846 in Owen County, Indiana to Phillip Allen. She died in 1901 in Jefferson County, Kansas. No records have been found naming her parents.

Step 2: Write a Research Summary

Records for Dovey as a married adult were found
Dovey’s obituary and death certificate from Kansas were sought. No death certificate found. Obituary did not name parents.
Owen County Library, Archives and Court house were searched. Extensive research was done, but not exhaustive; I did not document the sources that I used….so this work needs to be redone
1840 Census searched for Owen Co. Indiana Reynolds. 1 household found with female 15-19 years old (age Dovey would be), headed by William Reynolds.
William Reynolds died in 1856, leaving a widow Amy, and naming children Jane, Solomon and Edmond in his will. Dovey not mentioned
Possible father. No records found linking Dovey to this father

Step 3: Select the Right DNA Test

Autosomal DNA: Dovey was my 3^rd great grandmother. I have inherited approximately 3% of my autosomal DNA from her.
Mitochondrial DNA is not relevant to this case due to inheritance path.
Since she is a female, Y-DNA is not relevant.

Step 4: Select the Right Relative to Test

Autosomal DNA – test the closest living person to the mystery ancestor: Test my father or his sister (aunt) to get one generation closer.

Step 5: Complete Family Tree for Other Family Lines

DNA Match Analysis Strategies

Search DNA matches’ trees for “Reynolds” surname.
Each DNA company has a tool for searching your matches (23andme is not as good as others.)

Results of our search for “Reynolds” in matches’ trees: Look for Reynolds in key locations in Dovey’s life such as NC and IN, especially Owen Co. IN, and maybe KS:

Matches with Reynolds in their trees from New England, Canada, England, etc. probably NOT related.
Create a note for yourself, saying, for instance, “Maine Reynolds family” so you don’t waste time on probable irrelevant matches.

Match Summary

24 matches to William Reynolds’ descendants (27 cM – 8 cM)

10 matches from daughter Lucy
4 matches from daughter Diana
1 match from daughter Temperance
3 from son Solomon
2 from son Edmond
4 from daughter Deborah

DNA Preliminary Conclusions

DNA links my aunt to descendants of 6 of William Reynold’s children.
This does not prove that Dovey was William’s daughter. She could have been his niece or other close relative.
Aunt shares the correct number of cMs with the matches to be 4^th-5^th cousins with them.
Aunt’s shared matches with these Reynolds matches are on her paternal line – which is the correct side of the family.
More genealogical research could provide the definite link.

Case #2: Mysterious Leroy Porter

Step 1: Define Problem:

Leroy Porter was born in 1897 in France or PA
Married Ina Hill and died in Michigan.
Leroy was a teller of tall tales; family wants to know his origins, his parentage, and was he really from France?

Step 2: Research Summary

Death certificate (informant wife) says parents were Daniel Porter and Mary Baschley of PA.
Leroy cannot be found on any census prior to 1920 as Leroy Porter.
No trace of parents of those names found

Step 3: DNA Testing Options

Granddaughter Kathy took the autosomal DNA test.

Y-chromosome test not applicable for Kathy (there may be a candidate for Y DNA testing within the family)
Mitochondrial DNA not applicable

Step 4: Test the correct person:

Several of Leroy’s daughters are alive, so if they took an autosomal test, would be one generation closer.

Ancestry DNA match sorting options:

“Add to Group” option
Allows you to name the group, and add colored dots, up to 24 different colors
Notes field = enter free text notes about matches

Results

Evaluated trees of the possible matches from Leroy’s side. Two match groups identified:

Hedges family of PA
Crute family of PA

Can we find a marriage between these 2 families? Yes – Daniel Hedges married Alice Crute ca. 1894 probably Warren Co. PA.

More Genealogical Work

Sara found “LeRoy Hedges” in the 1900 Warren Co. PA Census!
She went through Kathy’s tree to find matches to Hedges/Crute family
Were the cMs within range for the relationships? Yes = 2^nd DNA points to Leroy Hedges being Leroy Porter.

Leroy Hedges = Leroy Porter Summary

Family broken up by 1910
Parents remarried
Siblings in orphanage
Leroy Hedges ran away and was not heard from again
Did he go to Michigan and marry Ina Hill as Leroy Porter?
No official name change document found
Could compare photographs if Hedges family has one…

Resources

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AncestryDNA Review and Breaking News! Updates Launched

by Lisa Cooke | Nov 20, 2014 | 01 What's New, Ancestry, Brick Wall, DNA

“This is really the first time a DNA testing company has so fully integrated genetics and genealogy. We can now find cousins in the database who do not share our particular genetics, but who do share some of the genetics of our common ancestor. This is huge.” -Diane Southard, Your DNA Guide

I blogged a couple of weeks ago about some changes taking place over at AncestryDNA. You will recall that they are planning to slash your match list to allow only “invited guests” to your personal DNA party. (Read that post to be reminded why this is a good thing.)

Ancestry has officially announced the launch of this feature update and reports that on average users will see an 80% reduction in the number of matches shown. I had a chance to look at the new site before it launched and one of my favorite features is the question mark that appears next to your match. Clicking on the question mark on your match page will bring up a menu of references to help you better understand the inner workings of matching at Ancestry, including those confidence levels that are a part of every relationship prediction. In this table below you can see that ancestry has tried to give you some fairly solid guidelines by which to assess the quality of your matches. You will want to focus on those matches with a confidence score of “High” or above to have the best chance of genealogical success. But an update to the matching feature is only the beginning of the new features at AncestryDNA. Today Ancestry announced “DNA Circles,” a tool that helps you identify others who share common ancestors with you. The new “DNA Circles” feature has the potential to impact the way you do genetic genealogy at Ancestry. Here’s why: Autosomal DNA (the kind that Ancestry is testing) has a spotty inheritance pattern. On average we only have half of the DNA of each of our parents, only 25% of our grandparents, only 12.5% of our great grandparents and so on. This means that AncestryDNA and its competitors (Family Tree DNA and 23andMe) are only able to genetically identify 50% of your genetic 4^th cousins. This means that there could be 50% MORE people in these databases that you are actually related to, people that should have been invited to your DNA party, but didn’t have a ticket. Now with DNA Circles, there is a metaphorical “after-party.” After parties are “hosted” by one of your relatives. Ancestry searches your pedigree and that of your matches back 7 generations looking for suitable hosts. An ancestor qualifies as a host if they have two or more descendants who hold an invitation. At this after-party you can meet some of these long lost cousins that, while related to you, lost their ticket to your DNA party. After-party invitations are provided to those who meet three very important qualifications:

They have their DNA attached to their PUBLIC family tree.
AND that PUBLIC family tree has the name of the hosting ancestor on it.
AND this person shares DNA with at least one other person who also meets the above two criteria.

Here’s an example. Below is an image of the new AncestryDNA home page. You can see I am a part of two DNA Circles (some of you will be much more popular and invited to several after-parties. For me–just the two for now). Let’s take a closer look at my DNA Circle hosted by my paternal 5^th great grandfather Minus Griggs (who knew the guy liked parties?!). Clicking on the DNA circle brings up this page where there are three things I want to show you:

This is your relationship to the host.
This is a list of the individuals who have passed the three criteria listed above and have been invited to this after-party.
This is the innovative part. You see that the first two matches (after me–I am listed first) have only “Tree Match” in this column. This means that these two people, both descendants of our host, Minus Griggs, didn’t ever appear on my DNA match list. We do not share enough DNA to be considered genetic relatives. However, the third member of the circle has the “DNA Match” designation, meaning that this match DOES appear on my match page. In fact, this is my ONLY DNA match in the circle (there are three others not shown here). That means that this DNA circle has connected me to FIVE other cousins. All because I share DNA and genealogy with the third member of this circle, and he shares DNA and genealogy with everyone else.

I can click on each circle member to see exactly how Ancestry THINKS we are related. This is my first opportunity to DOUBLE CHECK this relationship that Ancestry has handed me, to be sure that both my match and I really did receive tickets to the same after party.

Here is what that page looks like for me and one of my matches.

This is really the first time a DNA testing company has so fully integrated genetics and genealogy. We can now find cousins in the database who do not share our particular genetics, but who do share some of the genetics of our common ancestor. In my opinion, this is huge.

There is one catch, and it is going to be a big one for some of you. In order to see your DNA Circles, you have to be an Ancestry.com subscriber.

Even though I am excited about these changes, I can’t help but hope for just one step more. In order to identify these DNA Circles, Ancestry has identified pieces of DNA that can be fairly reliably assigned to a particular ancestor. There are likely others in the Ancestry database who have these pieces of DNA, we can call them partial tickets to the after-party, but who are lacking the second requirement: a pedigree documenting a relationship to that ancestor. I hope in the future the folks at Ancestry will honor those partial ticket holders, and allow them to the after-party, so we can sit around with our peanuts and pretzels and figure out how we are all related. Until then, I am going to enjoy the two after-parties hosted by my two generous ancestors.

Ready to walk through the process of using DNA for your genealogy? Let me be your guide! Check out my quick guides (left) Purchase each guide individually or pick up the bundle of all 4 for the best deal!

Visit my website to learn about expert consultations with me. You’ll get customized guidance on which tests to order and how to maximize your results for your genealogy research.

DNA Testing for Family History

by Lisa Cooke | Nov 20, 2016

From Diahan Southard, Your DNA Guide here at Genealogy Gems: DNA testing is one of the most personal ways to get involved in your family history. You have DNA from your parents, who have DNA from their parents, and so it goes, back into your greats and great-greats. The technology of genetic genealogy is all about tapping into that DNA record and pulling out information that might be useful in your family history. DNA can do this for you in two ways:

First, it connects you to places. These are places where your ancestors came from a hundred, a thousand, or tens of thousands of years ago.
Second, it connects you to people. These people are your genetic cousins, other living people who have taken the same DNA test that you took. The similarities in your DNA tell you that you share a common ancestor. You can then examine the pedigree of your match and work with them to help verify your family history, or give you new ideas about who your ancestors might be.

Types of DNA Tests for Family History

You have three choices of DNA tests, each with its own unique purpose.

Autosomal DNA – For any ancestor, male or female, who is fewer than 5 generations from you, you can take the autosomal DNA test at either Family Tree DNA, AncestryDNA, 23andMe, or MyHeritage to find out more about that individual. Remember with the autosomal DNA that you always want to test the oldest generation first. So anyone who does not have both of their parents living should take the autosomal DNA test.

mtDNA – If I want to know about a female ancestor, let’s say Mary West, I need to find Mary’s daughter’s daughter’s daughter’s, etc. child (male or female) to take the mitochondrial DNA (mtDNA) from Family Tree DNA.

YDNA – Essentially, if you want to know about a male ancestor, you need to find a direct male descendant to be tested. So if I want to know about my 3X great grandfather Morris Mitchell, I need to find Morris’s son’s son’s son, etc. until I find a living male with the Mitchell surname who can be tested on the Y chromosome DNA (mtDNA) test at Family Tree DNA.

DNA Testing Companies

There are several companies that test DNA for family history including:

Each of these companies offers a very similar autosomal DNA test, but each has its own unique tools and databases. Decide which company you want to test with by evaluating things like:

their website accessibility
their company goals
and especially the size of their database

You can see a table comparing these companies here.

Great (DNA) Expectations

The best thing you can do when setting out on your genetic genealogy journey is set good expectations. You can expect that the test will document the personal genetics of the person who takes it. By so doing, you are creating another genealogy record that will last for generations. This test will link you to your ancestors via your cousins. That means that you may take the test looking for ancestors, but what you get are cousins. It will take traditional genealogy work to turn those cousin connections into ancestral connections. Above all, expect that this is a growing industry, and what we know today is different than what we will know tomorrow, so enjoy the journey!

Genetic Genealogy for the Layman

There are several comprehensive books on Genetic Genealogy out there. However, for the layman who just wants to understand their DNA test results and get some additional value from them, an entire book full of scientific explanations can be overwhelming and daunting. The following email is one we receive regularly:

“Could you direct me to an understandable publication which explains dna results in layman’ terms ? Thank you” – Anne B.

Genealogy Gems Publications is proud to publish Diahan Southard’s wonderful series of DNA quick reference guides for understanding your DNA results in plain language, and helping you get the most out of the investment you made in testing.

8 Guides to Help You Understand and Use Your DNA Results

The complete collection of DNA quick reference guides cover:

The testing companies: AncestryDNA, 23andme, Family Tree DNA, MyHeritage
The tests: Autosomal, YDNA, Mitochondrial
How to find your ancestors using your DNA.

All guides are available in convenient digital download format.

Click here to shop now: Save on the set of 8 DNA quick reference guides at the Genealogy Gems store.

More DNA Resources from Genealogy Gems

Free Videos: Here’s a link to our DNA videos on YouTube with the author of the guides, Diahan Southard. Here’s a great one to start with:

Free Podcast: Diahan has a regular segment on the free Genealogy Gems Podcast where she answers your questions and provides invaluable insights into the latest in genetic genealogy.

Free Articles: You can browse the complete archive of DNA articles at Genealogy Gems. The most recent will appear first and then scroll down to read through the past articles.

DNA in the News

As of March 28, 2017, AncestryDNA customers can see if their ancestors belonged to about 300 different Genetic Communities, small migratory groups that can be identified by DNA. In the next free Genealogy Gems podcast episode #202, you will learn more about it straight from Ancestry’s Chief Scientific Officer, Catherine Ball. For more information on Genetic Communities, watch the video below:

Want to get tested? Get your AncestryDNA test here.

MyHeritage’s New Health+Ancestry DNA Kit

by Lisa Cooke | May 20, 2019 | 01 What's New, DNA, MyHeritage

New on the DNA Front: The new MyHeritage DNA Health + Ancestry test is now available and provides comprehensive health reports for conditions affected by genetics including heart disease, breast cancer, type 2 diabetes, and Alzheimer’s disease. Plus you’ll still get the genealogy tools for matching and discovering common ancestors. Read on to learn more about what health data is provided, how to order, the privacy policy, and more. Also keep in mind that DNA and health testing are a personal responsibility and decision, and the information provided below is for informational purposes only.

MyHeritage Expands to Health

From the MyHeritage press release: Tel Aviv, Israel & Lehi, Utah — MyHeritage, the leading global service for family history and DNA testing, announced today a major expansion of its DNA product line with the launch of the MyHeritage DNA Health + Ancestry test. The test provides a new dimension of genetic insight with comprehensive health reports that can empower future health and lifestyle choices. It is a superset of the current MyHeritage DNA Ancestry-Only test, and includes its pillar features: a percentage breakdown of ethnic origins and matching to relatives through shared DNA. MyHeritage is now the only global consumer DNA company to offer an extensive health and ancestry product in over 40 languages.

The launch of the Health + Ancestry product distinguishes MyHeritage as the only major service that bridges consumers’ past, present, and future: MyHeritage’s integrated suite of products enable users to discover their family history and ethnic origins, find new relatives, and receive valuable insights to help manage choices regarding their health that may impact their future well-being.

“Our Health + Ancestry test is the next step in the evolution of MyHeritage. After 16 years of changing lives for the better through family history research and genetic genealogy, we are excited to expand our mission and try to improve and save lives as well. Our vision is to integrate our successful family history technologies with the new health product in innovative ways that bridge heritage and heredity to deliver deeper insights for our users,” said Gilad Japhet, founder and CEO of MyHeritage. “We are proud to be part of a movement to democratize healthcare globally and make genetic testing accessible to millions of people, and allow them to discover what makes them unique.”

What Health Data is Included?

According to the company, The MyHeritage DNA Health + Ancestry test provides health reports that show users their risk of developing or carrying genetic conditions. Reports include conditions where specific genes contribute to the risk, such as hereditary breast cancer, late-onset Alzheimer’s disease, and late-onset Parkinson’s disease; conditions associated with multiple genes, such as heart disease, and type 2 diabetes; and carrier status reports on conditions that can be passed down from a couple to their children, such as Tay-Sachs disease and cystic fibrosis.

In total, MyHeritage’s Health + Ancestry test covers one of the most extensive ranges of conditions offered by an at-home DNA test: 11 Genetic Risk Reports, including a hereditary breast cancer (BRCA) report that tests 10 pathogenic variants; 3 Polygenic Risk Reports; and 15 Carrier Status Reports.

Taking the Test

MyHeritage DNA Health + Ancestry is a Laboratory Developed Test, processed in a CLIA certified and CAP accredited DNA lab in Texas. The at-home DNA test is an easy and painless cheek swab, and does not require spitting as some other tests do, which makes it more suitable and convenient for all populations, including older people.

Health reports only determine users’ genetic risk for the supported conditions. However, all users are required to complete a personal and family health history questionnaire, to ensure that each user receives the reports appropriate for them. MyHeritage works with PWNHealth, an independent physician network and genetic counseling service, to provide end-to-end physician oversight of the MyHeritage DNA Health + Ancestry test for all U.S. customers, which includes genetic counseling, if appropriate. PWNHealth’s physician oversight and genetic counseling fee is included in the total price.

Your Health Data is Private

Privacy is strictly enforced. All health data is protected by state-of-the-art encryption. Health report data is secured using additional password protection and is so secure that even MyHeritage employees cannot access it. MyHeritage has never licensed or sold user data, and has committed to never do so without obtaining explicit user consent. MyHeritage is the only consumer DNA company that has pledged to never sell data to insurance companies. It also applies a strict policy to prohibit use of its DNA services by law enforcement agencies.

Pricing & Ordering

The MyHeritage DNA Health + Ancestry kit is available at the price of $199 + shipping. Users who have already purchased a MyHeritage DNA test for ethnicity and genealogy matching can upgrade to receive health reports for $120. To order, visit the MyHeritage DNA website. An annual Health subscription is available as an optional add-on to the new DNA kit, which grants users access to new health reports as they are released. As a special benefit for the launch, the Health subscription is currently offered for free for the first twelve months and users can cancel it anytime.

Disclaimer

The new health product is not intended to independently diagnose, prevent, or treat any disease or condition or tell users anything about their current state of health in the absence of medical and clinical information.

The product is also not intended for making medical decisions, including prescription or dosing of medications. Users may need to obtain further services from their physician, a genetic counselor, or other healthcare provider, in order to obtain diagnostic results regarding the conditions or diseases indicated within the MyHeritage DNA health reports.

The health reports provide genetic risk information based on assessment of specific genetic variants but do not report on users’ entire genetic profile. The health reports do not detect all genetic variants related to a given disease, and the absence of a variant tested does not rule out the presence of other genetic variants that may be related to the disease.

For most diseases, currently known genes are only responsible for a portion of the overall risk. Other factors such as environment and lifestyle may affect the risk of developing a given disease and, depending on the condition, may be more relevant predictors.

If a user’s data indicate that the user is not at elevated genetic risk for a disease or condition, this should not be interpreted as meaning that the user is safe from developing the disease or condition. The opposite is also true; if a user’s data indicates that the user is at an elevated genetic risk for a disease or condition, it does not mean that the user will definitively develop the disease or condition. Any findings within the health reports should be confirmed and supplemented by additional medical and clinical testing as recommended by the user’s healthcare provider.

MyHeritage DNA Health + Ancestry is available globally except in a few countries that do not allow health-related consumer genetic testing. In the USA, it is available in all states except New York, New Jersey, and Rhode Island, where separate laboratory certifications are required and are currently being pursued. Altogether, MyHeritage DNA Health + Ancestry is now the genetic test for health available in the greatest number of languages and with the widest global reach.

MyHeritage Ltd.,
P.O.Box 50, 3 Ariel Sharon St.,
Or Yehuda, Israel

Disclosure: This article is a press release provided by MyHeritage. It is intended for informational purposes, and not intended as a promotion of DNA health tests. This article does contain affiliate links and Genealogy Gems will be compensated if you make a purchase after clicking on these links (at no additional cost to you).

Genealogy & Family Tree Video Classes

by Lisa Cooke | Jul 22, 2020

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