by Lisa Cooke | Nov 20, 2014 | 01 What's New, Ancestry, Brick Wall, DNA
“This is really the first time a DNA testing company has so fully integrated genetics and genealogy. We can now find cousins in the database who do not share our particular genetics, but who do share some of the genetics of our common ancestor. This is huge.” -Diane Southard, Your DNA Guide
I blogged a couple of weeks ago about some changes taking place over at AncestryDNA
. You will recall that they are planning to slash your match list 
to allow only “invited guests” to your personal DNA party. (Read that post to be reminded why this is a good thing.)
Ancestry has officially announced the launch of this feature update and reports that on average users will see an 80% reduction in the number of matches shown. I had a chance to look at the new site before it launched and one of my favorite features is the question mark that appears next to your match. Clicking on the question mark on your match page will bring up a menu of references to help you better understand the inner workings of matching at Ancestry, including those confidence levels that are a part of every relationship prediction. In this table below you can see that ancestry has tried to give you some fairly solid guidelines by which to assess the quality of your matches. You will want to focus on those matches with a confidence score of “High” or above to have the best chance of genealogical success. 
But an update to the matching feature is only the beginning of the new features at AncestryDNA. Today Ancestry announced “DNA Circles,” a tool that helps you identify others who share common ancestors with you. The new “DNA Circles” feature has the potential to impact the way you do genetic genealogy at Ancestry. Here’s why: Autosomal DNA (the kind that Ancestry is testing) has a spotty inheritance pattern. On average we only have half of the DNA of each of our parents, only 25% of our grandparents, only 12.5% of our great grandparents and so on. This means that AncestryDNA and its competitors (Family Tree DNA and 23andMe) are only able to genetically identify 50% of your genetic 4th cousins. This means that there could be 50% MORE people in these databases that you are actually related to, people that should have been invited to your DNA party, but didn’t have a ticket. Now with DNA Circles, there is a metaphorical “after-party.” After parties are “hosted” by one of your relatives. Ancestry searches your pedigree and that of your matches back 7 generations looking for suitable hosts. An ancestor qualifies as a host if they have two or more descendants who hold an invitation. At this after-party you can meet some of these long lost cousins that, while related to you, lost their ticket to your DNA party. After-party invitations are provided to those who meet three very important qualifications:
- They have their DNA attached to their PUBLIC family tree.
- AND that PUBLIC family tree has the name of the hosting ancestor on it.
- AND this person shares DNA with at least one other person who also meets the above two criteria.
Here’s an example. Below is an image of the new AncestryDNA home page. You can see I am a part of two DNA Circles (some of you will be much more popular and invited to several after-parties. For me–just the two for now). Let’s take a closer look at my DNA Circle hosted by my paternal 5th great grandfather Minus Griggs (who knew the guy liked parties?!). 
Clicking on the DNA circle brings up this page where there are three things I want to show you: 
- This is your relationship to the host.
- This is a list of the individuals who have passed the three criteria listed above and have been invited to this after-party.
- This is the innovative part. You see that the first two matches (after me–I am listed first) have only “Tree Match” in this column. This means that these two people, both descendants of our host, Minus Griggs, didn’t ever appear on my DNA match list. We do not share enough DNA to be considered genetic relatives. However, the third member of the circle has the “DNA Match” designation, meaning that this match DOES appear on my match page. In fact, this is my ONLY DNA match in the circle (there are three others not shown here). That means that this DNA circle has connected me to FIVE other cousins. All because I share DNA and genealogy with the third member of this circle, and he shares DNA and genealogy with everyone else.
I can click on each circle member to see exactly how Ancestry THINKS we are related. This is my first opportunity to DOUBLE CHECK this relationship that Ancestry has handed me, to be sure that both my match and I really did receive tickets to the same after party.
Here is what that page looks like for me and one of my matches.
This is really the first time a DNA testing company has so fully integrated genetics and genealogy. We can now find cousins in the database who do not share our particular genetics, but who do share some of the genetics of our common ancestor. In my opinion, this is huge.
There is one catch, and it is going to be a big one for some of you. In order to see your DNA Circles, you have to be an Ancestry.com subscriber.
Even though I am excited about these changes, I can’t help but hope for just one step more. In order to identify these DNA Circles, Ancestry has identified pieces of DNA that can be fairly reliably assigned to a particular ancestor. There are likely others in the Ancestry database who have these pieces of DNA, we can call them partial tickets to the after-party, but who are lacking the second requirement: a pedigree documenting a relationship to that ancestor. I hope in the future the folks at Ancestry will honor those partial ticket holders, and allow them to the after-party, so we can sit around with our peanuts and pretzels and figure out how we are all related. Until then, I am going to enjoy the two after-parties hosted by my two generous ancestors.
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by Diahan Southard | Oct 24, 2014 | 01 What's New, Ancestry, DNA, Jewish
Ancestry.com has improved the ability of AncestryDNA to find good matches for Jewish, Hispanic and other ancestries that maybe weren’t so precise before. Here’s the lowdown, quoted liberally from Ancestry.com’s press release:
The problem: Predicting genetic relatives among customers of Jewish and Hispanic descent and some other groups. “In DNA matching, we are looking for pieces of DNA that appear identical between individuals,” says the release. “For genealogy research we’re interested in DNA that’s identical because we’re both descended from a recent common ancestor. We call this identical by descent (IBD). This is what helps us to make new discoveries in finding new relatives, new ancestors, and collaborating on our research.”
“However, we also find pieces of DNA that are identical for another reason. At one extreme we find pieces of DNA that are identical because it is essential for human survival. At the other, we find pieces of DNA that are identical because two people are of the same ethnicity. We call these segments identical by state (IBS) because the piece of DNA is identical for a reason other than a recent common ancestor. This, we have found, often happens in individuals of Jewish descent.”
“The challenge in DNA matching is to tease apart which segments are IBD, and which ones are IBS….Most Jewish customers find that we predict them to be related to nearly every other Jewish customer in the database….Detecting which cousin matches were real and which ones were bogus has always been a challenge for these populations.”
First step toward a solution: “By studying patterns of matches across our more than half a million AncestryDNA customers, we found that in certain places of the genome, thousands of people were being estimated to share DNA with one another–likely a hallmark of a common ethnicity. Our scientific advancements… have allowed us to effectively “pan for gold” in our matches–by throwing out matches that appear to only be IBS, and keeping those that are IBD.”
“While the problem was more pronounced in customers of Jewish and some Hispanic descents, we observed this problem across all ethnic groups. So, all customers will see increased accuracy of their DNA matches, and significantly fewer ‘false’ matches.”
AncestryDNA results with better matches found by this method “will be available in the coming months,” says the release. They plan to email existing customers when results are ready.
by Lisa Cooke | Oct 19, 2014 | 01 What's New, Ancestry, DNA
You may recall from our recent DNA discussion on the Genealogy Gems podcast (Episode 168) that Ancestry.com recently discontinued their mtDNA and YDNA tests (the two that trace our direct maternal and direct paternal lines) to focus on autosomal DNA (which delivers information about both your mother’s and your father’s side of your ancestral tree).
Well, recently I attended an all-day meeting hosted by Ancestry.com: a summit to talk about current trends and accomplishments at Ancestry DNA
, and ideas about the future of DNA testing at Ancestry.com.
The meeting included a diverse group of Ancestry representatives, from CEO Tim Sullivan to members of the marketing, scientific, communications, and even computer science departments, as well as some of the top voices in genetic genealogy. It was an open and lively discussion, and I walked away with a few gems I want to share with you today.
More Powerful DNA Hints Coming
In AncestryDNA, the ‘shaky leaf” hints are meant to help you find a common ancestor between you and your DNA matches. The computer code behind the old hints was not very efficient. Lazy, in fact. It started at the bottom of your tree—and the bottom of your match’s tree—and slapped on a shaky leaf at the first sign of a shared common ancestor.
While this method worked for a large number of cases, it was leaving a lot of stones unturned. But the IT guys at Ancestry have beefed up the computer power, allowing them to cover a much greater distance through our trees and the trees of our matches before making a judgment about the best place to assign that shaky leaf.
The result? Better hints about how you and your match COULD be related. Remember, the leaf is still just a SUGGESTION on how you and your match might be related. It is not a crystal ball.
Did You Know?
- Ancestry DOES store your DNA samples in a secure location.
- Ancestry spent months designing their own DNA collection kit.
- Ancestry was able to attract some of the brightest scientists in the field of population genetics because of YOU. You with your documented pedigree charts and your willingness to help move this science of discovering our ancestors forward.
Looking Ahead
There is no question that the genetic genealogy industry is rapidly advancing, and our discussion with Ancestry certainly didn’t disappoint. While I will be sharing with you in future posts about some of the exciting changes, I do want you to be ready for one that buy anxiety medication online uk will be coming online fairly soon.
It has to do with your matches. If you have been tested by AncestryDNA, you may have been initially excited, then nearly immediately overwhelmed, by the number of individuals listed in your match page, all claiming to have some kind of connection to you and your family tree.
All three major genetic genealogy testing companies (AncestryDNA, Family Tree DNA, and 23andMe) are using basically the same laboratory methods to glean information from your DNA. What differs is how they use that data to draw conclusions about your ethnic heritage and about your relationships to other individuals. As it turns out, AncestryDNA has been reporting far more individuals as your relatives than it should have.
You can think of it like this: You have sent out tickets, in the form of your genetic code, to an exclusive party where you (of course!) are the star. However, you have lost the guest list and you are counting on the testing company to check the ticket of each guest before they enter your party to be sure they were really invited.
AncestryDNA was relatively new in the role of party bouncer, and in the interest of not turning away any VIP guests, they initially allowed guests into your party who had (gasp!) forged tickets!! But as AncestryDNA admits more guests, the experience it’s gained in party monitoring is starting to show.
You see, each of the forged tickets has some unique qualities that have started to send up red flags to the team of scientists at AncestryDNA. They are now in the process of carefully documenting what each forged ticket looks like and tossing those unwanted guests out on their ear.
The short of it: in the near future your match list at Ancestry will be much shorter. Which is good news to you, as it means only those invited genetic cousins will be around eating hors d’ oeuvres and ready to talk about your shared common ancestry.
Each testing company has its strengths and weaknesses. It was good to have a bit of insight into this one company and come to a greater understanding about why it is they do what they do. It is a great time to be in this young genetic genealogy industry, with so much room to grow and change. I will let you know when I find the next genetic gem.
Disclosure: This article contains affiliate links and Genealogy Gems will be compensated if you make a purchase after clicking on these links (at no additional cost to you). Thank you for supporting Genealogy Gems!
by Lisa Cooke | Jun 12, 2014 | 01 What's New, DNA
Michael Ibsen, a cabinet maker living in London, was recently awarded the title of “royal descendant” when researchers identified him as a direct maternal descendant of Ann of York. Why did this lucky man have an unsolicited team of researchers filling in 17 generations of his genealogy?
They were trying to identify a body.
A body discovered under a parking lot in Leichester, England.
According to an article in the Mail Online, thanks to the mitochondrial DNA (mtDNA) of Ibsen, that body has been identified as Richard the III. Researchers needed Ibsen because his mtDNA is EXACTLY the same as his 17th great grandmother, Ann of York. Because mothers pass their mtDNA to all of their children, and only the daughters pass it on to the next generation, Ann had exactly the same mtDNA as her brother, Richard.
With the positive identification in hand, researchers are now prepared to undertake a £100,000 project to discover the combination of letters in a four-digit code that makes up the genetic book that is (or was) Richard III. This process is called full genome sequencing. They are also planning to sequence Mr. Ibsen’s genome to see what shared segments may still remain.
What does this project have to do with you?
So what does this project have to do with you the genealogist who doesn’t have a team of researchers hammering out your 17th generation grandparents?
First, it is a win for genetic genealogy as mtDNA was used to unequivocally link past and future generations. Each story like this serves to increase buy soma medication online awareness for genetic genealogy, which means more people get tested, which means databases grow larger, which means you will find more matches, which means you will have more genealogical success. Plus, the comparison of the ancient Richard the III genome with the modern genome of Mr. Ibsen will be the first of its kind to try to identify shared segments of DNA after so many generations.
In a recent interview Michael Ibsen said, “I almost hope somewhere along the line they dig up some more people so others can be ancestors and descendants in the same sort of way. It is going to be an extraordinary experience.”
Someone needs to introduce Mr. Ibsen to genetic genealogy as that is EXACTLY what genetic genealogy is all about-but minus the digging up the bones part! Genetic genealogy is all about using the DNA of living people to reconstruct the DNA of your ancestors. It is about making connections among modern day genealogists that can help them answer questions about their relatives.
While a full genome sequence is not a practical genealogical tool for most genealogists, there are other kids of DNA tests that could help you answer genealogical questions.
You can find more information about a few famous people and their DNA here.
And learn even more by reading MNT’s article 3D model provides new insight into King Richard III’s spinal condition.
And don’t miss Lisa’s interview with Dr. Turi King who ran the DNA testing on King Richard III. Listen to Genealogy Gems Podcast episode 152 now.
by Lisa Cooke | Jan 13, 2014 | 01 What's New, DNA
It’s not uncommon for genetic DNA tests to reveal that you’re not related to people you thought you were. But here’s a twist I’ve never heard before.
A family who had a daughter by artificial insemination of the husband’s sperm eventually decided to do some DNA testing for family history. Imagine the wife’s shock when she discovered that her husband and daughter shared no DNA!
They got a bigger shock when they did a little research. Apparently the biological father worked at the lab that handled the family’s insemination process. The man is dead now, but it appears he may have deliberately swapped in his own sample for the father’s.
Of course lots of questions have come up–including how many other children may have received the DNA of a man who was a convicted kidnapper.
My heart goes out to this family and to others who now fear their genetic fatherhood was hijacked. Read the full story here (it’s popped up in several news outlets now, but I first saw it at KUTV.com).
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